Melatonin reduces lens oxidative stress level in STZ-induced diabetic rats through supporting glutathione peroxidase and reduced glutathione values
نویسندگان
چکیده
منابع مشابه
Lens Capsular Glutathione Level and Glutathione Peroxidase Activity Among Diabetic Patients +
To evaluate the level of glutathione (GSH) and gluthathione peroxidase (GSH-Px) activity in the anterior ule of patients with cataract in diabetic patients with meticulous control and in patients with senile cataract. The anterior lens capsules in 18 eyes with diabetes under tight glycemic control with cataract (Group A) 6 eyes with senile cataract (Group B) were collected in phacoemulsificatio...
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Objective: The purpose of the present study was investigation of eight weeks high intensity interval (HIIT) along with curcumin supplementation on liver Glutathione Peroxidase (GPX) Activity & Malondialdehyde (MDA) Concentration among diabetic male rats. Materials and Methods: Thirty-two male mice were divided to four groups of control-diabetic, exercise-diabetic, supplementary-diabetic, and e...
متن کاملThe effect of date aqua extract and melatonin on diabetic neuropathy in STZ-induced diabetic rats
Introduction: Diabetes mellitus is often associated with chronic neuropathy, a condition which is due to the disturbance in the function of peripheral nervous system. Studying the effects of antioxidants in relieving neuropathy is of a great clinical importance. The aim of this study was to compare the effect of aqua extract of date and Melatonin in preventing neuropathic hyperalgesia in Strept...
متن کاملRelationship between malondialdehyde level and glutathione peroxidase activity in diabetic rats.
BACKGROUND This investigation describes the relationship between glutathione peroxidase activities, an antioxidant enzyme, and the oxidative status in diabetic rat blood. METHODS Malondialdehyde level and glutathione peroxidase activity were measured by spectrophotometric techniques. RESULTS AND CONCLUSIONS Malondialdehyde content in the diabetic rats group was increased compared to that in...
متن کاملSuperoxide dismutase, catalase and glutathione peroxidase activities in the brain of streptozotocin induced diabetic rats.
Brain antioxidant enzymes, superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPX) levels were studied in the brains of early diabetic (72 hr) and long term diabetic (one month) rats. Diabetes was induced by injecting streptozotocin (50 mg/kg, i.p.) in citrate buffer. One group of diabetic rats was treated with insulin (1U/day/animal). The results indicate that early diabeti...
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ژورنال
عنوان ژورنال: Journal of Cellular Neuroscience and Oxidative Stress
سال: 2016
ISSN: 2149-7222
DOI: 10.37212/jcnos.334113